Solitärt plasmocytom
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However, some evidence indicates that factors such as genetics, viral infections, and inhaled irritants may contribute.
Potential risk factors for the condition older age, being male, and being African American. AJR Am J Roentgenol (full text) - Pubmed citation
Related articles: Bone tumours
The differential diagnosis for bone tumors is dependent on the age of the patient, with a very different set of differentials for the pediatric patient.
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INTRODUCTION
Plasma cell neoplasms (plasma cell dyscrasias) are a group of entities characterized by the neoplastic proliferation of clonal plasma cells, typically producing a monoclonal immunoglobulin.
In fact, this appearance is so characteristic that it may obviate the need for a diagnostic biopsy.
Signal characteristics include:
- T1: hypo- to isointense
- T2: iso- to hyperintense to muscle
- T1 C+ (Gd): variable enhancement
Treatment and prognosis
Excision of the tumor and its extent is done, with chemoradiotherapy as an adjuvant.
A may progress into multiple myeloma. It is not meant to be comprehensive and should be used as a tool to help the user understand and/or assess potential diagnostic and treatment options. As this condition may develop into multiple myeloma, it is important to closely monitor the condition.
There is still no known cause of solitary plasmacytoma.
It is seen as curvilinear low signal intensity areas within the lesion, giving an appearance of sulci in the brain. This typically occurs within , so it is important to closely monitor individuals for signs of multiple myeloma.
Individuals with SBP may be at a higher risk of progressing to multiple myeloma than those with SEP.
However, some suggests that overall survival rates for SBP and SEP may not be significantly different.
A 2019 retrospective analysis of solitary plasmacytoma cases in the United Kingdom and Brazil suggests a 5-year survival rate of almost .
Solitary plasmacytoma refers to a single mass of abnormal plasma cells that can occur in bone or soft tissue.
Dimopoulos MA, Kiamouris C, Moulopoulos LA. Solitary plasmacytoma of bone and extramedullary plasmacytoma. All rights reserved.
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Clin. It is not intended to be medical advice or a substitute for the medical advice, diagnosis, or treatment of a health care provider based on the health care provider's examination and assessment of a patient's specific and unique circumstances.It does NOT include all information about conditions, treatments, medications, side effects, or risks that may apply to a specific patient. The use of this information is governed by the Terms of Use, available at https://www.wolterskluwer.com/en/know/clinical-effectiveness-terms. UpToDate, Inc. and its affiliates disclaim any warranty or liability relating to this information or the use thereof.
Oncol. Health experts usually consider solitary plasmacytoma as an early form of multiple myeloma. Local recurrence is less than 5% and dissemination is seen in 35-70% of patients. The disease may progress to multiple myeloma, with a bad prognosis.
General imaging differential considerations include:
- 1.
Hematol. This involves focusing radiation, similar to X-rays, on the plasmacytoma to kill the abnormal cells.